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Cardiovascular clinical trials

Advancing heart health through clinical research

Exploring a new path to heart health

Early access to potential new treatments. Be among the first to benefit from medical advancements designed to improve

Expert medical care and monitoring. Receive ongoing support from leading healthcare professionals throughout the trial, ensuring your well-being at every step.

Making a difference for future patient. Your participation helps shape the future of cardiovascular medicine, providing insights that lead to better treatments for others.

What to expect on your visit

Warm welcome and check in

Our team will will greet you and guide you though the process.

Comfortable waiting area

Relax with seating, refreshments and Wi-Fi whilst you wait.

Meet your specialist

A dedicated professional will explain everything and answer any questions.

Clear instructions

We’ll walk you through each step so you know exactly what to expect

Time for questions

You’ll have the opportunity to ask anything about your participation

Follow-up guidance

We’ll provide details on the next steps and any necessary follow-up visits.

Your questions answered

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  • A clinical trial protocol is a comprehensive plan that outlines the study’s objectives, design, methodology, statistical considerations, and organisation. It specifies: 

    • The purpose of the study 
    • Eligibility criteria for participants 
    • Details of tests, procedures, medications, and dosages 
    • The schedule of activities 
    • Information to be collected about participants 

    This protocol ensures the study is conducted consistently and safely across all participants.  

  • Clinical trials encompass various study types, including: 

    • Prevention Trials: Explore methods to prevent diseases in individuals who have not had them or to prevent recurrence. 
    • Treatment Trials: Test new treatments, drug combinations, or approaches to therapy. 
    • Diagnostic Trials: Seek better tests or procedures for diagnosing specific conditions. 
    • Screening Trials: Evaluate ways to detect diseases or health conditions. 
    • Quality of Life Trials: Aim to improve comfort and life quality for individuals with chronic illnesses. 

    Many trials compare a new product or therapy to existing treatments or placebos to determine effectiveness. Potential participants are informed beforehand if placebos are part of the study design.

  • Participating in a clinical trial offers several potential benefits: 

    • Access to New Treatments: You may receive investigational therapies not yet available to the public, potentially improving your health condition. 
    • Contribute to Medical Research: Your involvement aids in understanding how treatments work across different populations, helping to develop better therapies for future patients. 
    • Comprehensive Care: Participants receive close monitoring and additional healthcare assessments related to the study. 
    • Voluntary Participation: You can withdraw from the study at any time without any obligation. 

    Each study has specific eligibility criteria, so not everyone who applies will be accepted.  

  • Clinical trials progress through several phases, each designed to answer specific research questions: 

    • Phase 1: Involves a small group (20-80 participants), often healthy volunteers or patients with advanced diseases. The focus is on evaluating safety, identifying side effects, determining safe dosage ranges, and understanding how the body processes the investigational product. This phase typically lasts several months, with about 70% of studies advancing to Phase 2. 
    • Phase 2: Enrols 100-300 participants with the condition under study to further assess safety and effectiveness. These trials may be randomised and controlled, comparing the investigational product to standard treatments or placebos. Blinding is often used to prevent bias. Phase 2 studies usually take up to two years, with approximately 33% progressing to Phase 3. 
    • Phase 3: Includes larger groups (thousands of participants) to confirm effectiveness, monitor side effects, and compare the investigational product to standard treatments. These randomised and blinded trials can last from one to four years, with 25-30% successfully leading to regulatory approval submissions. 
    • Phase 4: Conducted after regulatory approval, these post-marketing studies gather additional information on risks, benefits, and optimal use in various populations over extended periods. Findings can influence whether a product remains on the market or if usage guidelines need adjustments.  
  • A clinical trial is a medical research study involving volunteers to explore new ways to prevent, detect, or treat diseases, illnesses or ailments. These studies assess investigational treatments, which may include new drugs, combinations of drugs, new delivery methods for existing medications, or medical devices. Before approval, these treatments undergo rigorous testing to ensure they are safe and effective. Each trial follows a detailed protocol outlining the study’s purpose, participant criteria, procedures, and duration. A principal investigator, often a medical doctor, leads the research team, which includes various healthcare professionals. Participation is entirely voluntary, and diverse involvement is crucial to understand different responses to the investigational product. 

Trial details overview

What’s this clinical trial about?

We’re investigating an investigational medicine focusing on its potential to reduce major adverse cardiovascular events—like heart attacks and strokes—in adults with elevated lipoprotein levels.

Elevated lipoprotein is a key factor in the development of atherosclerotic cardiovascular disease, a condition where plaque builds up inside your arteries, leading to serious heart problems.

Who Can Join?

  • Adults aged 55 and above.
  • Those with a diagnosis of cardiovascular disease or those at risk of facing their first heart event.
  • Those who have Hypertension
  • Tobacco users
  • If you have Diabetes
  • Suffer with High cholesterol
  • Suffer with Chronic Kidney Disease

Who Should Not Participate?

  • Individuals with New York Heart Association class IV heart failure.
  • Anyone who has undergone a procedure to remove lipoproteins from their blood.
  • Individuals with an active infection or a major disease that is not stable or well-managed.

Study Details

  • Duration: Approximately 4 years
  • Goal: To determine if investigational medicine can make a meaningful difference in preventing heart-related problems by reducing the effects of elevated lipoprotein levels.

Why is this Clinical Trial important?

Cardiovascular diseases are the leading cause of death globally. By participating, you’re contributing to research on how heart disease is treated.

How to Apply:

To determine your eligibility for this clinical trial, please fill out our online eligibility form. This brief questionnaire will help us understand your medical history and pain management needs.

 

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Available Panthera Locations

Ready to take part?

Join this trial and help shape future treatments today

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