Weight loss clinical trials

Are you struggling to lose weight despite repeated past efforts?

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We’re evaluating the effectiveness of an investigational injectable medication in supporting weight loss

Early access to potential new treatments. Be among the first to benefit from medical advancements designed to improve

Expert medical care and monitoring. Receive ongoing support from leading healthcare professionals throughout the trial, ensuring your well-being at every step.

Making a difference for future patients. Your participation helps shape the future of weight loss medicine, providing insights that lead to better treatments for others.

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Receptionist assisting visitor at clinic desk

What to expect on your visit

Warm welcome and check in

Our team will will greet you and guide you though the process.

Comfortable waiting area

Relax with seating, refreshments and Wi-Fi whilst you wait.

Meet your specialist

A dedicated professional will explain everything and answer any questions.

Clear instructions

We’ll walk you through each step so you know exactly what to expect

Time for questions

You’ll have the opportunity to ask anything about your participation

Follow-up guidance

We’ll provide details on the next steps and any necessary follow-up visits.

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Your questions answered

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A clinical trial protocol is a comprehensive plan that outlines the study’s objectives, design, methodology, statistical considerations, and organisation. It specifies:
- The purpose of the study
- Eligibility criteria for participants
- Details of tests, procedures, medications, and dosages
- The schedule of activities
- Information to be collected about participants
This protocol ensures the study is conducted consistently and safely across all participants.
What is a clinical trial protocol?

A clinical trial protocol is a comprehensive plan that outlines the study’s objectives, design, methodology, statistical considerations, and organisation. It specifies:

The purpose of the study

Eligibility criteria for participants

Details of tests, procedures, medications, and dosages

The schedule of activities

Information to be collected about participants

This protocol ensures the study is conducted consistently and safely across all participants.
Clinical trials encompass various study types, including:
- Prevention Trials: Explore methods to prevent diseases in individuals who have not had them or to prevent recurrence.
- Treatment Trials: Test new treatments, drug combinations, or approaches to therapy.
- Diagnostic Trials: Seek better tests or procedures for diagnosing specific conditions.
- Screening Trials: Evaluate ways to detect diseases or health conditions.
- Quality of Life Trials: Aim to improve comfort and life quality for individuals with chronic illnesses.
Many trials compare a new product or therapy to existing treatments or placebos to determine effectiveness. Potential participants are informed beforehand if placebos are part of the study design.
What types of clinical trials are available?

Clinical trials encompass various study types, including:

Prevention Trials: Explore methods to prevent diseases in individuals who have not had them or to prevent recurrence.

Treatment Trials: Test new treatments, drug combinations, or approaches to therapy.

Diagnostic Trials: Seek better tests or procedures for diagnosing specific conditions.

Screening Trials: Evaluate ways to detect diseases or health conditions.

Quality of Life Trials: Aim to improve comfort and life quality for individuals with chronic illnesses.

Many trials compare a new product or therapy to existing treatments or placebos to determine effectiveness. Potential participants are informed beforehand if placebos are part of the study design.
Participating in a clinical trial offers several potential benefits:
- Access to New Treatments: You may receive investigational therapies not yet available to the public, potentially improving your health condition.
- Contribute to Medical Research: Your involvement aids in understanding how treatments work across different populations, helping to develop better therapies for future patients.
- Comprehensive Care: Participants receive close monitoring and additional healthcare assessments related to the study.
- Voluntary Participation: You can withdraw from the study at any time without any obligation.
Each study has specific eligibility criteria, so not everyone who applies will be accepted.
Why should I participate in a clinical trial?

Participating in a clinical trial offers several potential benefits:

Access to New Treatments: You may receive investigational therapies not yet available to the public, potentially improving your health condition.

Contribute to Medical Research: Your involvement aids in understanding how treatments work across different populations, helping to develop better therapies for future patients.

Comprehensive Care: Participants receive close monitoring and additional healthcare assessments related to the study.

Voluntary Participation: You can withdraw from the study at any time without any obligation.

Each study has specific eligibility criteria, so not everyone who applies will be accepted.
Clinical trials progress through several phases, each designed to answer specific research questions:
- Phase 1: Involves a small group (20-80 participants), often healthy volunteers or patients with advanced diseases. The focus is on evaluating safety, identifying side effects, determining safe dosage ranges, and understanding how the body processes the investigational product. This phase typically lasts several months, with about 70% of studies advancing to Phase 2.
- Phase 2: Enrols 100-300 participants with the condition under study to further assess safety and effectiveness. These trials may be randomised and controlled, comparing the investigational product to standard treatments or placebos. Blinding is often used to prevent bias. Phase 2 studies usually take up to two years, with approximately 33% progressing to Phase 3.
- Phase 3: Includes larger groups (thousands of participants) to confirm effectiveness, monitor side effects, and compare the investigational product to standard treatments. These randomised and blinded trials can last from one to four years, with 25-30% successfully leading to regulatory approval submissions.
- Phase 4: Conducted after regulatory approval, these post-marketing studies gather additional information on risks, benefits, and optimal use in various populations over extended periods. Findings can influence whether a product remains on the market or if usage guidelines need adjustments.
What do the different phases of a clinical trial mean?

Clinical trials progress through several phases, each designed to answer specific research questions:

Phase 1: Involves a small group (20-80 participants), often healthy volunteers or patients with advanced diseases. The focus is on evaluating safety, identifying side effects, determining safe dosage ranges, and understanding how the body processes the investigational product. This phase typically lasts several months, with about 70% of studies advancing to Phase 2.

Phase 2: Enrols 100-300 participants with the condition under study to further assess safety and effectiveness. These trials may be randomised and controlled, comparing the investigational product to standard treatments or placebos. Blinding is often used to prevent bias. Phase 2 studies usually take up to two years, with approximately 33% progressing to Phase 3.

Phase 3: Includes larger groups (thousands of participants) to confirm effectiveness, monitor side effects, and compare the investigational product to standard treatments. These randomised and blinded trials can last from one to four years, with 25-30% successfully leading to regulatory approval submissions.

Phase 4: Conducted after regulatory approval, these post-marketing studies gather additional information on risks, benefits, and optimal use in various populations over extended periods. Findings can influence whether a product remains on the market or if usage guidelines need adjustments.
A clinical trial is a medical research study involving volunteers to explore new ways to prevent, detect, or treat diseases, illnesses or ailments. These studies assess investigational treatments, which may include new drugs, combinations of drugs, new delivery methods for existing medications, or medical devices. Before approval, these treatments undergo rigorous testing to ensure they are safe and effective. Each trial follows a detailed protocol outlining the study’s purpose, participant criteria, procedures, and duration. A principal investigator, often a medical doctor, leads the research team, which includes various healthcare professionals. Participation is entirely voluntary, and diverse involvement is crucial to understand different responses to the investigational product.

What is a clinical trial?

A clinical trial is a medical research study involving volunteers to explore new ways to prevent, detect, or treat diseases, illnesses or ailments. These studies assess investigational treatments, which may include new drugs, combinations of drugs, new delivery methods for existing medications, or medical devices. Before approval, these treatments undergo rigorous testing to ensure they are safe and effective. Each trial follows a detailed protocol outlining the study’s purpose, participant criteria, procedures, and duration. A principal investigator, often a medical doctor, leads the research team, which includes various healthcare professionals. Participation is entirely voluntary, and diverse involvement is crucial to understand different responses to the investigational product.

Trial details overview

What’s this clinical trial about?

Obesity is a chronic, complex medical condition that can affect long-term health and wellbeing. Panthera Clinical Research is looking conduct a weight loss clinical trial evaluating the effectiveness of an investigational injectable medication when used alongside lifestyle guidance.

This potential study will follow a similar research approach to modern injectable weight-loss studies currently available, but participation is at no cost.

What does participation involve?

If you meet the eligibility criteria for an approved study and choose to participate, study activities may include:

Receiving an investigational injectable study medication or placebo
Following study-related lifestyle guidance, including diet and physical activity recommendations
Ability to self-inject or receive assistance from a trained caregiver
Attending regular clinic visits for assessments, lab tests, and questionnaires
Participation for the full duration of the study

Who May Be Eligible?

You may be able to take part if you:

Are 18 years of age or older
Have a BMI of 30 kg/m² or higher, or
Have a BMI of 27 to under 30 kg/m² and at least one weight-related condition, such as:
- High blood pressure
- Abnormal cholesterol or lipid levels
- Obstructive sleep apnea
- Cardiovascular disease (including heart disease or prior stroke)

Additional eligibility criteria will apply and will be reviewed by the study team.

Who May Not Be Eligible?

You may not be able to take part if you:

Are pregnant or breastfeeding, or unable to follow contraceptive requirements
Have had prior or planned surgical treatment for obesity
Have experienced significant recent weight changes
Are currently participating in another weight-loss program or using weight-loss medications
Are currently using or have recently used injectable treatments for diabetes or weight loss
Have certain medical conditions or lab results that may affect study participation
Are currently participating in another clinical trial.
Have a history of pancreatitis

A full eligibility review will be completed during screening

Why take part?

Contribute to Weight Loss Research
Your participation helps researchers evaluate the effectiveness of investigational injectable approaches for weight management.

Experienced Research Oversight
Potential participants are supported by a qualified clinical research team throughout the study.

No Cost to Participate
All study-related visits, assessments, and investigational medication are provided at no cost.

Compensation for Time & Travel
If you are eligible for participation, compensation for time and reimbursement for reasonable travel expenses may be available.

About the Study

This clinical trial is designed to evaluate how effective an investigational injectable medicine may be in supporting weight loss when combined with diet and physical activity guidance.

With many injectable weight-loss treatments now available, continued research is needed to better understand which approaches may have the greatest impact on weight management. This potential study will look to contribute to that ongoing research.

Apply Now