Norovirus Clinical Trials

Help research new ways to help prevent Norovirus

Apply Now

Play a key role in the fight against Norovirus

Early access to potential new treatments. Be among the first to benefit from medical advancements designed to improve

Expert medical care and monitoring. Receive ongoing support from leading healthcare professionals throughout the trial, ensuring your well-being at every step.

A key aim is to understand whether an investigational medicine can help reduce flare-ups (also known as exacerbations), which are sudden worsening of symptoms that can lead to hospital visits.

Apply Now

Panthera becomes the world’s first clinical trial site to administer Valneva’s inactivated COVID-19 vaccine

What to expect on your visit

Warm welcome and check in

Our team will will greet you and guide you though the process.

Comfortable waiting area

Relax with seating, refreshments and Wi-Fi whilst you wait.

Meet your specialist

A dedicated professional will explain everything and answer any questions.

Clear instructions

We’ll walk you through each step so you know exactly what to expect

Time for questions

You’ll have the opportunity to ask anything about your participation

Follow-up guidance

We’ll provide details on the next steps and any necessary follow-up visits.

Apply Now

Your questions answered

Apply Now

A clinical trial protocol is a comprehensive plan that outlines the study’s objectives, design, methodology, statistical considerations, and organisation. It specifies:
- The purpose of the study
- Eligibility criteria for participants
- Details of tests, procedures, medications, and dosages
- The schedule of activities
- Information to be collected about participants
This protocol ensures the study is conducted consistently and safely across all participants.
What is a clinical trial protocol?

A clinical trial protocol is a comprehensive plan that outlines the study’s objectives, design, methodology, statistical considerations, and organisation. It specifies:

The purpose of the study

Eligibility criteria for participants

Details of tests, procedures, medications, and dosages

The schedule of activities

Information to be collected about participants

This protocol ensures the study is conducted consistently and safely across all participants.
Clinical trials encompass various study types, including:
- Prevention Trials: Explore methods to prevent diseases in individuals who have not had them or to prevent recurrence.
- Treatment Trials: Test new treatments, drug combinations, or approaches to therapy.
- Diagnostic Trials: Seek better tests or procedures for diagnosing specific conditions.
- Screening Trials: Evaluate ways to detect diseases or health conditions.
- Quality of Life Trials: Aim to improve comfort and life quality for individuals with chronic illnesses.
Many trials compare a new product or therapy to existing treatments or placebos to determine effectiveness. Potential participants are informed beforehand if placebos are part of the study design.
What types of clinical trials are available?

Clinical trials encompass various study types, including:

Prevention Trials: Explore methods to prevent diseases in individuals who have not had them or to prevent recurrence.

Treatment Trials: Test new treatments, drug combinations, or approaches to therapy.

Diagnostic Trials: Seek better tests or procedures for diagnosing specific conditions.

Screening Trials: Evaluate ways to detect diseases or health conditions.

Quality of Life Trials: Aim to improve comfort and life quality for individuals with chronic illnesses.

Many trials compare a new product or therapy to existing treatments or placebos to determine effectiveness. Potential participants are informed beforehand if placebos are part of the study design.
Participating in a clinical trial offers several potential benefits:
- Access to New Treatments: You may receive investigational therapies not yet available to the public, potentially improving your health condition.
- Contribute to Medical Research: Your involvement aids in understanding how treatments work across different populations, helping to develop better therapies for future patients.
- Comprehensive Care: Participants receive close monitoring and additional healthcare assessments related to the study.
- Voluntary Participation: You can withdraw from the study at any time without any obligation.
Each study has specific eligibility criteria, so not everyone who applies will be accepted.
Why should I participate in a clinical trial?

Participating in a clinical trial offers several potential benefits:

Access to New Treatments: You may receive investigational therapies not yet available to the public, potentially improving your health condition.

Contribute to Medical Research: Your involvement aids in understanding how treatments work across different populations, helping to develop better therapies for future patients.

Comprehensive Care: Participants receive close monitoring and additional healthcare assessments related to the study.

Voluntary Participation: You can withdraw from the study at any time without any obligation.

Each study has specific eligibility criteria, so not everyone who applies will be accepted.
Clinical trials progress through several phases, each designed to answer specific research questions:
- Phase 1: Involves a small group (20-80 participants), often healthy volunteers or patients with advanced diseases. The focus is on evaluating safety, identifying side effects, determining safe dosage ranges, and understanding how the body processes the investigational product. This phase typically lasts several months, with about 70% of studies advancing to Phase 2.
- Phase 2: Enrols 100-300 participants with the condition under study to further assess safety and effectiveness. These trials may be randomised and controlled, comparing the investigational product to standard treatments or placebos. Blinding is often used to prevent bias. Phase 2 studies usually take up to two years, with approximately 33% progressing to Phase 3.
- Phase 3: Includes larger groups (thousands of participants) to confirm effectiveness, monitor side effects, and compare the investigational product to standard treatments. These randomised and blinded trials can last from one to four years, with 25-30% successfully leading to regulatory approval submissions.
- Phase 4: Conducted after regulatory approval, these post-marketing studies gather additional information on risks, benefits, and optimal use in various populations over extended periods. Findings can influence whether a product remains on the market or if usage guidelines need adjustments.
What do the different phases of a clinical trial mean?

Clinical trials progress through several phases, each designed to answer specific research questions:

Phase 1: Involves a small group (20-80 participants), often healthy volunteers or patients with advanced diseases. The focus is on evaluating safety, identifying side effects, determining safe dosage ranges, and understanding how the body processes the investigational product. This phase typically lasts several months, with about 70% of studies advancing to Phase 2.

Phase 2: Enrols 100-300 participants with the condition under study to further assess safety and effectiveness. These trials may be randomised and controlled, comparing the investigational product to standard treatments or placebos. Blinding is often used to prevent bias. Phase 2 studies usually take up to two years, with approximately 33% progressing to Phase 3.

Phase 3: Includes larger groups (thousands of participants) to confirm effectiveness, monitor side effects, and compare the investigational product to standard treatments. These randomised and blinded trials can last from one to four years, with 25-30% successfully leading to regulatory approval submissions.

Phase 4: Conducted after regulatory approval, these post-marketing studies gather additional information on risks, benefits, and optimal use in various populations over extended periods. Findings can influence whether a product remains on the market or if usage guidelines need adjustments.
A clinical trial is a medical research study involving volunteers to explore new ways to prevent, detect, or treat diseases, illnesses or ailments. These studies assess investigational treatments, which may include new drugs, combinations of drugs, new delivery methods for existing medications, or medical devices. Before approval, these treatments undergo rigorous testing to ensure they are safe and effective. Each trial follows a detailed protocol outlining the study’s purpose, participant criteria, procedures, and duration. A principal investigator, often a medical doctor, leads the research team, which includes various healthcare professionals. Participation is entirely voluntary, and diverse involvement is crucial to understand different responses to the investigational product.

What is a clinical trial?

A clinical trial is a medical research study involving volunteers to explore new ways to prevent, detect, or treat diseases, illnesses or ailments. These studies assess investigational treatments, which may include new drugs, combinations of drugs, new delivery methods for existing medications, or medical devices. Before approval, these treatments undergo rigorous testing to ensure they are safe and effective. Each trial follows a detailed protocol outlining the study’s purpose, participant criteria, procedures, and duration. A principal investigator, often a medical doctor, leads the research team, which includes various healthcare professionals. Participation is entirely voluntary, and diverse involvement is crucial to understand different responses to the investigational product.

Trial details overview

What’s this clinical trial about?

We are conducting a clinical research trial to evaluate the safety and effectiveness of a Norovirus vaccine for adults aged over 60. By participating, you can play a key role in the fight against Norovirus, the leading cause of acute gastroenteritis worldwide.

Who Can Join?

Adults aged over 60 years old.

Why Norovirus Matters

Norovirus is a highly contagious virus that causes sudden onset of severe stomach pain, nausea, vomiting, and diarrhoea. It affects millions of people globally every year, and there’s currently no vaccine available.

Who Should Not Participate?

You may not be able to take part if you:

Have had acute gastroenteritis within 14 days before your first clinic visit (if you’ve been sick recently, you may still qualify at a later date).
Have a reported history of substance abuse.
Have a reported history of congenital or acquired immunodeficiency.
Have participated in another clinical study within 90 days prior to your first clinic visit.

Why Participate?

By joining this trial, you’ll contribute to investigational research focused on the first vaccine for Norovirus. As a participant in this clinical research trial, you will receive compensation for your participation and reimbursement for travel expenses related to clinic visits.

Apply Now